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Genistein

(HB2775)
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Product overview

Name Genistein
Purity >98%
Description Protein tyrosine kinase inhibitor and PPARγ agonist. Phytoestrogen.
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews (1) References (3)
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Biological Data

Biological description Phytoestrogen. Protein tyrosine inhibitor and PPARγ and PPARα agonist (Ki values = 5.7 nM at PPARγ). Also binds estrogen receptors to exert weak estrogenic activity. Shows variety of biological actions.

Solubility & Handling

Storage instructions -20°C (desiccate)
Solubility overview

Soluble in DMSO (100 mM)

Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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x
More Info

Dilution

x
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x
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Chemical Data

Purity >98%
Chemical name 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4 H-1-benzopyran-4-one
Molecular Weight 270.24
Chemical structure Genistein Chemical Structure
Molecular Formula C15H10O5
CAS Number 446-72-0
PubChem identifier 5280961
SMILES OC1=CC=C(C=C1)C1=COC2=C(C(O)=CC(O)=C2)C1=O
InChi InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H
InChiKey TZBJGXHYKVUXJN-UHFFFAOYSA-N
MDL number MFCD00016952

References for Genistein

References are publications that support the biological activity of the product

  • Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review.

    Wang L et al (2014) Biochem Pharmacol 92(1) : 73-89.
    Read more (PubMedID: 25083916)

  • Genistein increases epidermal growth factor receptor signaling and promotes tumor progression in advanced human prostate cancer.

    Nakamura H et al (2011) PLoS One 6(5) : e20034.
    Read more (PubMedID: 21603581)

  • Genistein, a specific inhibitor of tyrosine-specific protein kinases.

    Akiyama T et al (1987) J Biol Chem 262(12) : 5592-5.
    Read more (PubMedID: 3106339)

3 Item(s)

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Grouped product items
Order: HB2775
Pack PriceQty
10mg
$36
50mg
$141
Protein tyrosine kinase inhibitor and PPARγ agonist. Phytoestrogen.
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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