Actinomycin D

(HB1477)

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Product overview

Name Actinomycin D
Purity >98%
Description RNA polymerase inhibitor. Apoptosis inducer.
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Biological Data

Biological description RNA polymerase inhibitor and RNA synthesis inhibitor. DNA intercalating agent. Shows antitumor and cytotoxic effects. Also induces apoptosis.

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in DMSO (50 mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

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Chemical Data

Purity >98%
Chemical name 2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
Molecular Weight 1255.43
Molecular Formula C62H86N12O16
CAS Number 50-76-0
PubChem identifier 2019
SMILES CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C
InChiKey RJURFGZVJUQBHK-LIAOQTPJSA-N
MDL number MFCD00005033
Appearance Red shiny crystals