Stem Cell Reagents & Small Molecule Modulators
★ Popular stem cell reagents ★ Categories & pathways ★ Why Hello Bio ★ Reviews ★ Citations ★ Choosing a stem cell reagent ★ Stem cell culture guides | Browse all stem cell reagents
Stem cell reagents and small molecule modulators are essential for controlling self-renewal, proliferation and differentiation during stem cell culture in vitro. Researchers working with embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), adult stem cells and cancer stem cells (CSCs) rely on precise pathway modulation to direct cell fate, improve survival and support reproducible culture conditions.
Hello Bio supplies high-quality, affordable stem cell reagents and small molecules targeting key signalling pathways including Wnt, TGF-β/Activin, Notch, Hedgehog and retinoic acid. Our reagents are priced to support academic and grant-funded research — often up to 50% lower than standard suppliers — without compromising quality or performance.
Browse all stem cell reagents See stem cell reagent price comparisons →
Popular Stem Cell Reagents & Small Molecules
Quick access to widely used stem cell reagents for differentiation, reprogramming and pathway control. Popular picks below are chosen for high usage across protocols — with consistent quality and affordability.
→ Browse the full range of stem cell reagents
Browse Stem Cell Culture & Signalling Pathway Reagents
Browse products by biological process or pathway to quickly find reagents that match your experimental goals:
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Stem cell processes |
Key pathways used in stem cell protocols |
Why Choose Hello Bio for Stem Cell Reagents?
Hello Bio supplies reliable stem cell reagents and small molecules with clear documentation and reproducible performance — at accessible pricing (often ~50% lower than standard suppliers) without compromising quality.
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Affordable pricing
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Quality & consistency
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Trusted by researchers
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Try before you buy
Free Trial Program
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Browse all stem cell reagents See stem cell reagent price comparisons →
Trusted Stem Cell Reagents Used by Researchers Worldwide
Researchers rely on Hello Bio for affordable pricing, quick delivery and reliable performance in cell culture workflows.
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★★★★★
“We purchased the ROCK inhibitor Y-27632 to use in protocols related to iPSC-derived cardiomyocytes and it worked as expected. Cheaper than alternative vendors and quick delivery too!” Researcher, IMDEA, Spain (Y-27632) |
★★★★★
“Quick delivery, excellent results! Tested ROCKi Y-27632 for cryopreservation of organoids and yielded promising results! Highly recommend!” Researcher, University of Alabama, USA (Y-27632) |
Stem Cell Small Molecules Cited in Peer-Reviewed Publications
Hello Bio stem cell reagents are used in peer-reviewed research. Selected examples are below:
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Nature Neuroscience
Thermally induced neuronal plasticity in the hypothalamus mediates heat tolerance |
Cell Death Discovery
Parkinson's associated protein DJ-1 regulates intercellular communication via extracellular vesicles in oxidative stress |
Choosing the Right Stem Cell Reagent
Selection depends on your cell type, workflow stage (maintenance vs differentiation), and whether you’re optimising survival during handling. These quick pointers link to commonly used options:
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If your priority is cell survival during passaging / cryopreservation |
If you’re working in iPSC reprogramming or Wnt-driven protocols |
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If you’re supporting neuronal differentiation workflows |
★ Stem cell culture guide: practical overview & protocol guidance
Stem Cell Culture Guides & Resources
Practical resources from our PhD-qualified technical team to support stem cell experimental planning and reagent selection:
★ The role of small molecules in stem cell biology
How small molecules are used to control signalling pathways during stem cell culture and differentiation.
★ Neural stem cells & small molecules
Mini-review covering key small molecule tools used in neural stem cell workflows.
★ Stem cell culture guide: practical overview & protocol guidance

