Potent and selective 5-HT6 antagonist (pKi = 9.02-8.92 at 5-HT6). Shows > 200-fold selective over 55 other receptors, enzymes and ion channels. Increases levels of the neurotransmitters glutamate, aspartate, dopamine and noraderenaline in the rat front cortex and hippocampus. Shows anticonvulsant actions. Active in vivo
Solubility & Handling
Storage instructions
room temperature (desiccate)
Solubility overview
Soluble in DMSO (100mM) or ethanol (50mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists