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Solubility & Handling
| Storage instructions | -20°C |
| Solubility overview | Soluble in water (1 mg/ml) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use |
Chemical Data
| Chemical name | CTCNDMTDEECLNFCHQDVIW (modifications: Disulfide bridge between 1 - 15, 3 - 11) |
| Chemical structure | ![Sarafotoxin S6c | [121695-87-2] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Sarafotoxin S6c | [121695-87-2]") |
| Molecular Formula | C103H147N27O37S5 |
| Sequence (one letter) | CTCNDMTDEECLNFCHQDVIW |
| Modifications | Disulfide bridge between 1 - 15, 3 - 11 |
| PubChem identifier | 71456935 |
| SMILES | CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC3=CN=CN3)NC(=O)[C@@H]4CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H]5CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N4)CC6=CC=CC=C6)CC(=O)N)CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC5=O)CC(=O)N)CC(=O)O)CCSC)[C@@H](C)O)CC(=O)O)CCC(=O)O)CCC(=O)O)[C@@H](C)O)N |
| InChiKey | LXPHPKVWHQLBBA-JHOSIGDNSA-N |
References for Sarafotoxin S6c
References are publications that support the biological activity of the product
-
Distinct endothelin-B receptors mediate the effects of sarafotoxin S6c and IRL1620 in the ileum
Miasiro N et al (1998) J Cardiovasc Pharmacol 31 Suppl 1 : S175-8 -
Characterization of cloned human endothelin receptors
Williams DL Jr et al (1993) Life Sci 53(5) : 407-14 -
Sarafotoxin S6c: an agonist which distinguishes between endothelin receptor subtypes
Williams DL Jr et al (1991) Biochem Biophys Res Commun 175(2) : 556-61
Selective ETB receptor agonist
![Sarafotoxin S6c | [121695-87-2] Chemical Structure](https://media-m2stage.hellobio.com/media/catalog/product//h/b/hb3533_1.png "Sarafotoxin S6c | [121695-87-2]")
Understanding purity and quality - a guide for life scientists
