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RN 1747

(HB1186)
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Product overview

Name RN 1747
Purity >98%
Description Selective TRPV4 agonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (1)
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Biological Data

Biological description Selective TRPV4 agonist (EC50 values are 0.77, 4.0 and 4.1 µM for human, mouse and rat TRPV4 respectively). Displays selectivity for TRPV4 over TRPM8, TRPV1 and TRPV3. Also TRPM8 antagonist (IC50 = 4.0 µM).

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in DMSO (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name 1-(4-Chloro-2-nitrophenyl)sulfonyl- 4-benzylpiperazine
Molecular Weight 395.87
Chemical structure RN 1747 [1024448-59-6] Chemical Structure
Molecular Formula C17H18ClN3O4S
CAS Number 1024448-59-6
PubChem identifier 5068295
SMILES C1CN(CCN1CC2=CC=CC=C2)S(=O)(=O)C3=C(C=C(C=C3)Cl)[N+](=O)[O-]
InChi InChI=1S/C17H18ClN3O4S/c18-15-6-7-17(16(12-15)21(22)23)26(24,25)20-10-8-19(9-11-20)13-14-4-2-1-3-5-14/h1-7,12H,8-11,13H2
InChiKey ZNLVYSJQUMALEO-UHFFFAOYSA-N
MDL number MFCD04154169

References for RN 1747

References are publications that support the biological activity of the product

  • Identification and characterization of novel TRPV4 modulators.

    Vincent F et al (2009) Biochem Biophys Res Commun 389(3) : 490-4.
    Read more (PubMedID: 19737537)

1 Item

Grouped product items
Order: HB1186
Pack PriceQty
5mg
$65
10mg
$120
25mg
$258
50mg
$512
100mg
$934
Selective TRPV4 agonist
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Standard: $35

Hazardous: $35

Shipped on ice: $35

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