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Biological Data
| Biological description | Selective ROCK (Rho-kinase) inhibitor (IC50 values are 14, 780 and 1940 nM for ROCK1, RSK and p70S6K respectively). |
Solubility & Handling
| Storage instructions | +4°C |
| Solubility overview | Soluble in DMSO (100mM) or ethanol (25mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 4-[4-(Trifluoromethyl)phenyl]-N-(6- Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tet rahydro-3-pyridinecarboxamide |
| Molecular Formula | C21H16F4N4O2 |
| PubChem identifier | 11373846 |
| SMILES | O=C1CC(C2=CC=C(C(F)(F)F)C=C2)C(C(NC3=C(F)C=C(NN=C4)C4=C3)=O)=C(C)N1 |
| InChiKey | OLIIUAHHAZEXEX-UHFFFAOYSA-N |