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Biological Data
| Biological description | Potent, selective ROCK inhibitor (IC50 value = 11.8 nM). Glycyl analog of the ROCK inhibitor H 1152 dihydrochloride. |
Solubility & Handling
| Storage instructions | room temperature (desiccate) |
| Solubility overview | Soluble in water (100mM) or DMSO (50mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | (S)-(+)-4-Glycyl-2-methyl-1-[(4-met hyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-dia zepine dihydrochloride |
| Molecular Formula | C18H24N4O3S.2HCl |
| PubChem identifier | 56972177 |
| SMILES | CC1=CN=CC2=C1C(S(N3CCCN(C(CN)=O)C[C@@H]3C)(=O)=O)=CC=C2.Cl.Cl |
| InChiKey | ILDBNQGLZFSHQZ-UTLKBRERSA-N |
Potent, selective ROCK inhibitor
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