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β-Amyloid Peptide (25-35) (human)

(HB8524)
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Product overview

Name β-Amyloid Peptide (25-35) (human)
Biological description

β-Amyloid (25-35) is a synthetic peptide fragment of the amyloid beta protein. It shows neurotoxic activity.

Purity >95%
Description β-Amyloid (25-35) protein fragment
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (2) Reviews References (3)
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Biological Data

Application notes

Please see our Amyloid Beta Protocol

Solubility & Handling

Storage instructions -20°C
Solubility overview Freely soluble in H2O.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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x
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Dilution

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x
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Chemical Data

Purity >95%
Chemical name GSNKGAIIGLM
Molecular Weight 1060.27
Chemical structure Amyloid beta 25-35 TFA [131602-53-4] Chemical Structure
Molecular Formula C45H81N13O14S
Sequence (one letter) GSNKGAIIGLM
Sequence (three letter) H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH
Modifications N/A
CAS Number 131602-53-4
PubChem identifier 10843733
SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CO)NC(=O)CN
InChiKey WIHBNMPFWRHGDF-SLVFWPMISA-N
MDL number MFCD00133076
Appearance Lyophilized White solid
Protein length 11

References for β-Amyloid Peptide (25-35) (human)

References are publications that support the biological activity of the product

  • Effect of Beta-amyloid (25-35) on mitochondrial function and expression of mitochondrial permeability transition pore proteins in rat hippocampal neurons

    Ren R et al (2011) J Cell Biochem 112(5) : 1450-7
    Read more (PubMedID: 21321998)

  • Abeta(31-35) and Abeta(25-35) fragments of amyloid beta-protein induce cellular death through apoptotic signals: Role of the redox state of methionine-35

    Clementi ME et al (2005) FEBS Lett 579(13) : 2913-8
    Read more (PubMedID: 15890345)

  • Amyloid-beta(25-35)-induced memory impairments correlate with cell loss in rat hippocampus

    Stepanichev MY et al (2004) Physiol Behav 80(5) : 647-55
    Read more (PubMedID: 14984798)

3 Item(s)

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Order: HB8524
Pack PriceQty
1mg
$122
β-Amyloid (25-35) protein fragment
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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