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Biological Data
| Biological description | Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor. Anti-tumor compound. GSK-3beta (glycogen synthase kinase-3beta) inhibitor. Apoptosis inhibitor. Apoptosis inducer. Angiogenesis inhibitor. |
Solubility & Handling
| Storage instructions | +4°C |
| Solubility overview | Soluble in DMSO |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one |
| Chemical structure | |
| Molecular Formula | C16H11N3O3 |
| InChiKey | OLUKILHGKRVDCT-UHFFFAOYSA-N |
| Appearance | Yellow to brown powder |
Potent CDK1 inhibitor. Also shows activity at GSK-3β